Our research focuses on elucidating the mechanistic roles of food-derived bioactive compounds in the modulation of disease-related pathways. We are particularly interested in how phytochemicals from edible plants influence oxidative stress, inflammation, and cell survival mechanisms at the molecular level.
Currently, our work centres on the antioxidant and health-promoting properties of bioactive compounds derived from Passiflora edulis (passion fruit) and Cleome gynandra (maman). By integrating experimental and computational approaches, we aim to identify key metabolites responsible for biological activity and to understand their interactions with molecular targets involved in disease-associated pathways.
Our research employs a multidisciplinary strategy that combines in vitro antioxidant and biochemical assays with LC–MS-based metabolomic profiling, network pharmacology, molecular docking, and molecular dynamics simulations. This integrated framework enables us to link food processing and extraction conditions to chemical composition, bioactivity, and molecular mechanisms, thereby supporting the development of scientifically validated functional foods and nutraceuticals.